Everything about Beryllium Fluoride totally explained
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Beryllium fluoride is the
chemical compound with the
formula BeF
2. It is the
beryllium compound with the greatest amount of ionic character (due to the high
electronegativity of
fluorine), but even so it isn't considered ionic by many chemists. This synthetic material is the principal precursor for the manufacture of
beryllium metal, which is obtained by reduction of BeF
2 at 1300°C:
» BeF
2 + Mg → Be + MgF
2
Molecular BeF
2, is isoelectronic with
CO2 and
SiO2 and as found in the gas-phase above 1160 °C is a linear molecule with a Be-F distance of 177 pm.. The difference between the ambient temperature structures of BeF
2 and CO
2 reflects the decreased tendency of alkali metals to form multiple bonds. An analogy exists between BeF
2 and AlF
3: both adopt extended structures at mild temperature.
Applications
Beryllium fluoride is used in biochemistry, particularly protein crystallography, since it binds in some of the same ways as phosphate does.
ADP and beryllium fluoride together tend to bind to
ATP sites and inhibit protein action, making it possible to crystallise proteins in the bound state.
Safety
All beryllium compounds are highly toxic. Beryllium fluoride is very
soluble in water and is thus absorbed easily; as mentioned above, it inhibits ATP uptake. The
LD50 in mice is about 100mg/kg by ingestion and 1.8mg/kg by intravenous injection.
Further Information
Get more info on 'Beryllium Fluoride'.
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